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Kelly, P.A., Wang, H., Napoli, K.L., Kahan, B.D., and Strobel, H.W.: "Metabolism of Cyclosporine by Cytochromes P450 3A9 and 3A4."
European Journal of Drug Metabolism and Pharmacokinetics.
24: 321-328, 1999. |
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Antonovic, L., Hodek, P., Smrcek, S., Novák, P., Sulc, M., and Strobel, H.W.: "Heterobifunctional Photoaffinity Probes for Cytochrome P450 2B."
Archives of Biochemistry and Biophysics.
370: 208-215, 1999. |
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Boehme, C.L., Strobel,H.W.: "High-performance liquid chromatographic methods for the analysis of haloperidol and chlorpromazine metabolism in vitro by purified cytochrome P450 isoforms."
Journal of Chromatography B.
718: 259-266, 1998. |
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Thompson, C. M., Kawashima, H. and Strobel, H.W.: "Isolation of Partially Purified P450 2D18 and Characterization of Activity Toward the Tricyclic Antidepressants Imipramine and Desipramine."
Archives of Biochemistry and Biophysics.
359: 115-121, 1998. |
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Vasquez, H. and Strobel, H.W.: "Identification Of Cytochrome P450s In Human Glioma Cell Line."
International Journal of Oncology.
12: 1291-1294, 1998. |
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Geng, J. and Strobel, H.W.: "Expression, induction, and regulation of the cytochrome P450 monooxygenase system in the rat glioma C6 cell line."
Brain Research.
784:276-283, 1998. |
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Cvrk, T. and Strobel, H.W.: "Photoaffinity Labeling of Cytochrome P4501A1 with Azidocumene: Identification of Cumene Hydroperoxide Binding Region."
Archives of Biochemistry and Biophysics.
349:95-104, 1998. |
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Geng, J. and Strobel, H.W.: "Expression and Induction of P450 1A1 and P450 2D Subfamily in the Rat Glioma C6 Cell Line."
Brain Research.
774:11-19, 1997. |
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Kawashima, H., Kusunose, E., Thompson, C.M. and Strobel, H.W.: "Protein Expression, Characterization and Regulation of CYP4F4 and CYP4F5 Cloned from Rat Brain."
Archives of Biochemistry and Biophysics.
347:148-154, 1997. |
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Wang, H. and Strobel, H.W.: "Regulation of CYP3A9 Gene Expression by Estrogen and Catalytic Studies Using Cytochrome P450 3A9 Expressed in E. coli."
Archives of Biochemistry and Biophysics.
344:365-372, 1997. |
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Strobel, H.W., Geng, J., Kawashima, H. and Wang, H.: "Cytochrome P450-Dependent Biotransformation of Drugs and Other Xenobiotic Substrates in Neural Tissue."
Drug Metabolism Reviews.
29:1079-1105, 1997. |
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Baum, L.O., Strobel, H.W.: "Regulation of Expression of Cytochrome P-450 2D mRNA in Rat Brain with Steroid Hormones."
Brain Research.
765:67-73, 1997. |
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Thompson, C.M., Bernhard, A.E. and Strobel, H.W.: "Barbiturate Induced Expression of Neuronal Nitric Oxide Synthase in the Rat Cerebellum."
Brain Research.
754:142-146, 1997. |
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Yu, X.C., and Strobel, H.W.: "Hydroperoxide-Mediated Cytochrome P450-Dependent 8-Anilino-1- Naphthalenesulfonic Acid Destruction, Product Formation and P450 Modification."
Molecular and Cellular Biochemistry.
167:159-168, 1997. |
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Hodgson, A.V. and Strobel, H.W.: "Quantitation of FAD-dependent Cytochrome P450 Reductase Activity by Photoreduction."
Analytical Biochemistry.
243:154-157, 1996. |
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Kawashima, H., Sequeira, D.J., Nelson, D.R. and Strobel, H.W.: "Genomic cloning and protein expression of a novel rat brain cytochrome P450 CYP2D18 catalyzing imipramine N-demethylation."
Journal of Biological Chemistry.
271:28176-28180, 1996. |
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Vasquez, H.G. and Strobel, H.W.: "Effect of Cytochrome P450 Inducers on Expression of Oncogenes and a Tumor Suppressor Gene in Human Colon Cancer Cells."
International Journal of Oncology.
9:427-431, 1996. |
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Sequeira, D.J. and Strobel, H.W.: "In Vitro Metabolism of Imipramine by Brain Microsomes: Effects of Inhibitors and Exogenous Cytochrome P450 Reductase."
Brain Research.
738:24-31, 1996. |
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Cvrk, T., Hodek, P. and Strobel, H.W.: "Identification and Characterization of Cytochrome P450 1A1 Amino Acid Residues Interacting with a Radiolabeled Photoaffinity Diazido-benzphetamine Analogue."
Archives of Biochemistry and Biophysics.
330:142-152, 1996. |
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Yu, X.C., Liang, C. and Strobel, H.W.: "Kinetics of Substrate Reaction in the Course of Hydroperoxide-Mediated Inactivation of Cytochrome P450 1A1."
Biochemistry.
35:6289-6296, 1996. |
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Yu, X. C. and Strobel, H.W.: "Interactions of 8-Anilino-1-Naphthalenesulfonic Acid (ANS) and Cytochrome P450 2B1: Role of ANS as an Effector as well as a Reporter Group."
Molecular and Cellular Biochemistry.
162:89-95, 1996. |
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Bergh, A.F. and Strobel, H.W.: "Anatomical Distribution of NADPH-Cytochrome P450 Reductase and Cytochrome P450 2D Forms in Rat Brain: Effects of Xenobiotics and Sex Steroids."
Molecular and Cellular Biochemistry.
162:31-41, 1996. |
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Wang, H., Kawashima, H. and Strobel, H.W.: "cDNA Cloning of a Novel CYP3A from Rat Brain."
Biochemical and Biophysical Research Communications.
221:157-162, 1996. |
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Hodgson, A.V. and Strobel, H.W.: "Characterization of the FAD Binding Domain of Cytochrome P450 Reductase."
Archives of Biochemistry and Biophysics.
325:99-107, 1996. |
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Kawashima, Hidenori and Strobel, H.W.: "cDNA Cloning of Three New Forms of Rat Brain Cytochrome P450 Belonging to the CYP4F Subfamily."
Biochemical and Biophysical Research Communications.
217:1137-1144, 1995. |
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Strobel, H.W., Kawashima, H., Geng, J., Sequeira, D., Bergh, A., Hodson, A.V., Wang, H. and Shen, S.: "Expression of multiple forms of brain cytochrome P450."
Toxicology Letters.
82/83:639-643, 1995. |
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Ahmed, S.S., Napoli, K.L., and Strobel, H.W.: "Oxygen radical formation during cytochrome P450-catalyzed cyclosporine metabolism in rat and human liver microsomes at varying hydrogen ion concentrations."
Molecular and Cellular Biochemistry.
151: 131-140, 1995. |
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Sequeira, D.J., and Strobel, H.W.: "High-performance liquid chromatographic method for the analysis of imipramine metabolism in vitro by liver and brain microsomes."
Journal of Chromatography B.
673:251-258, 1995. |
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Kawashima, H. and Strobel, H.W.: "cDNA cloning of a novel rat brain cytochrome P450 belonging to the Cyp 2D subfamily."
Biochemical and Biophysical Research Communications.
209:535-540, 1995. |
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Yu, X.-C., Shen, S., and Strobel, H.W.: "Denaturation of cytochrome P450 2B1 by guanidine hydrochloride and urea: Evidence for a metastable intermediate state of the active site."
Biochemistry.
34:5511-5517, 1995. |
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Geng, J, and Strobel, H.W.: "Identification of inducible mixed function oxidase system in rat glioma C6 cell line."
Journal of Neurochemistry.
65:554-563, 1995. |
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Hodek, P., and Strobel, H.W.: "Preparation of [3H]-labelled benzphetamine photoaffinity probes for cytochrome P450."
Journal of Labeled Compounds and Radiopharmaceuticals.
36:321-329, 1995. |
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Yuan, W., White, T.B., White, J.W., Strobel, H.W., and Backes, W.L.: "Relationship between hydrocarbon structure and induction of cytochrome P450: Effect on RNA levels."
Xenobiotica.
25:9-16, 1995. |
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Shen, S., and Strobel, H.W.: "Probing the putative cytochrome P450 and cytochrome c-binding sites on NADPH-cytochrome P450 reductase by anti-peptide antibodies."
Biochemistry.
33:8807-8812, 1994. |
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Hodek, P., and Strobel, H.W.: "Synthesis and Characterization of azidobenzphetamine analogues of the cytochrome P450 substrate benzphetamine."
Bioorganic Chemistry.
22:253-267, 1994. |
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Geng, J., and Strobel, H.W.: "Identification of cytochromes P450 1A2, 2A1, 2C7, 2E1 in rat glioma C6 cell line by RT-PCR and specific restriction enzyme digestion."
Biochemical and Biophysical Research Communications.
197:1179-1184, 1993. |
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Ahmed, S. S., Strobel, H. W., Napoli, K. L., and Grevel, J.: "Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporin A and FK-506 in rat and human liver microsomes."
Journal of Pharmacology & Experimental Therapeutics.
265:1047-1054, 1993. |
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Shen, S., and Strobel, H.W.: "Role of lysine and arginine residues of cytochrome P450 in the interaction between cytochrome P4502B1 and NADPH-cytochrome P450 reductase."
Archives of Biochemistry and Biophysics.
304:257-265, 1993. |
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Serino, F., Grevel, J., Napoli, K. L., Kahan, B. D., and Strobel, H. W.: "Generation of oxygen free radicals during the metabolism of cyclosporine A: cause-effect relationship with metabolism inhibition."
Molecular and Cellular Biochemistry.
122:101-112, 1993. |
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Hodgson, A.V., White, T.B., White, J.W., and Strobel, H.W.: "Expression analysis of the mixed function oxidase system in rat brain by the polymerase chain reaction."
Molecular and Cellular Biochemistry.
120:171-179, 1993. |
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Roy, D., Bernhardt, A. Strobel, H.W., and Liehr, J. G.: "Catalysis of the oxidation of steroid and stilbene estrogens to estrogen quinone metabolites by the b-naphthoflavone-inducible cytochrome P450IA family."
Archives of Biochemistry and Biophysics.
296:450-456, 1992. |
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Shen, S., and Strobel, H.W.: "The role of cytochrome P450 lysine residues in the interaction between cytochrome P4501A1 and NADPH-cytochrome P450 reductase."
Archives of Biochemistry and Biophysics.
294:83-90, 1992. |
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Bergh, A.F., and Strobel, H.W.: "Reconstitution of the brain mixed function oxidase system: purification of NADPH-cytochrome P450 reductase and partial purification of cytochrome P450 from whole rat brain."
Journal of Neurochemistry.
59:575-581, 1992. |
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Hammond, D.K., Bjercke, R.J., Langone, J.J. and Strobel, H.W.: "Metabolism of nicotine by rat liver cytochromes P450: Assessment utilizing monoclonal antibodies to nicotine and cotinine."
Drug Metabolism and Disposition.
19:804-808, 1991. |
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Hammond, D.K., and Strobel, H.W.: "Ethoxyresorufin O-deethylase activity in intact human cells."
Toxicology in Vitro.
6:41-46, 1991. |
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Nadler, S.G., and Strobel, H.W.: "Identification and characterization of an NADPH cytochrome P450 reductase derived peptide involved in binding to cytochrome P450."
Archives of Biochemistry and Biophysics.
290:277-284, 1991. |
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Deodutta, R., Strobel, H.W., and Liehr, J.G.: "Cytochrome b5-mediated redox cycling of estrogen."
Archives of Biochemistry and Biophysics.
285:331-338, 1991. |
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Stralka, D.J., and Strobel, H.W.: "Characterization of cytochrome P450-dependent dimethylhydrazine metabolism in human colon microsomes."
Cancer.
68:2363-2369, 1991. |
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White, T.B., Hammond, D.K, Vasquez, H., and Strobel, H.W.: "Expression of two cytochromes P450 involved in carcinogen activation in a human colon cell line."
Molecular and Cellular Biochemistry.
102:61-69, 1991. |
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Schmucker, D.L., Wang, R.K., Snyder, D., Strobel, H.W., and Marti, U.: "Caloric restriction affects liver microsomal monooxygenases differentially in aging male rats."
Journal of Gerontology.
46:B23-27, 1991. |
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Bjercke, R.J., Hammond, D.K., Strobel, H.W., and Langone, J.J.: "Interaction of cotinine with rat hepatic microsomal P450: Comparison with metyrapone and immunomodulation of cotinine and metyrapone binding by monoclonal anti-cotinine antibodies."
Drug Metabolism and Disposition.
18:759-764, 1990. |
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Kurzban, G.P., Howarth, J., Palmer, G., and Strobel, H.W.: "NADPH-cytochrome P450 reductase: the physical properties and redox behavior in the absence of the FAD moeity."
Journal of Biological Chemistry.
265:12272-12279, 1990. |
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Hammond, D.K., and Strobel, H.W.: "Human colon tumor cell line LS174T drug metabolizing system."
Molecular and Cellular Biochemistry.
93:95-105, 1990. |
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Liehr, J.G., Roy, D., Ari-Ulubelen, A., Bui, Q.D., Weisz, J., and Strobel, H.W.: "Effect of chronic estrogen treatment of Syrian hamsters on microsomal enzymes mediating formation of catechol estrogens and their redox cycling: Implications for carcinogenesis."
Journal of Steroid Biochemistry.
35:555-560, 1990. |
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